Table 2 Studies exploring surgical measures in osteoporotic patients undergoing total knee arthroplasty (BMD = Bone Mineral Density)
From: Osteoporosis in the setting of knee arthroplasty: a narrative review
| Â | Author | Year | Results |
|---|---|---|---|
Cemented vs. cementless components | Linde et al. | 2022 | BMD was decreased for cemented components by 8.6% and 4.2% in the medial and anterior regions, respectively, until 24-month follow-up. BMD was increased for cementless components by 1.8% and 7.4% in the medial and anterior regions, respectively, until 24-month follow-up. |
Dubin et al. | 2024 | The cementless cohort had a 5-year periprosthetic fracture risk following TKA of 7.8% (95% CI, 5.56 to 10.98) in comparison to 4.30% in the cemented cohort (85% CI, 3.98 to 4.65) (P < 0.0001). | |
Ryan et al. | 2024 | Cementless fixation was associated with a lower revision rate in men, and it showed a higher rate of revision in women > 65 years of age | |
Mobile- vs. fixed-bearing components | Minoda et al. | 2010 | Prevention of BMD loss after TKA with mobile-bearing component compared to significant BMD loss of the femur with fixed-bearing component |
Ueyama et al. | 2020 | No difference was found in peri-prosthetic BMD changes between mobile- and fixed-bearing prostheses in patients undergoing oral bisphosphonate therapy. The BMD changes results are likely affected by oral bisphosphonate therapy. | |
Uncemented trabecular metal vs. cemented tibial components | Minoda et al. | 2010 | Less decrease in BMD in the lateral aspect of the tibia with trabecular metal components (6.7% ± 22.9% vs −36.8% ± 24.2%; p = 0.002). |
Hydroxyapatite coating of tibial component | Petersen et al. | 2005 | No significant effect was found on bone remodeling pattern of the proximal tibia. |
Uncemented porous-coated component | Petersen et al. | 1995 | Increased BMD by 22% proximal to the fixation pegs |
PCL retention | Ishii et al. | 2017 | No substantial effect was found on the BMD of the proximal femur and tibia. |
Medial peg position | Minoda et al. | 2022 | The closer the tibial medial peg was to the cortex, the larger the BMD loss in the medial part of the tibia at 2Â years postoperatively. |
Porous titanium construct Regenerex and porous coated (PPS) tibial tray | Winther et al. | 2016 | Both groups maintained peri-prosthetic BMD in lateral, medial and distal aspects below the central stem regions, with up to 8.1% and 6.5% increase at 12Â months for the PPS and Regenerex, respectively. |